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RPA70 Antibody

RPA70 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRPA70 Primary Polyclonal Antibody
Also known asRPA70 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRPA70
SpecificityThis is a highly specific antibody against RPA70
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RPA70
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It can also play a role in telomere maintenance, RPA contains a conserved four cysteine-type zinc-finger motif, RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair, RPA plays an important role in DNA replication, Replication protein A (RPA), The DNA binding domain lies in the middle of RPA 70 kDa subunit and comprises two structurally homologous subdomains oriented in tandem, The RPA 70 kDa subunit binds to ssDNA and mediates interactions with many cellular and viral proteins, The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of an ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA, a highly conserved eukaryotic protein, is a heterotrimeric SSB, mitochondria, phages and viruses, recombination and repair, which mediates the transition of RPA-ssDNA interaction to a stable RPA-ssDNA complex in a redox-dependent manner, The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DRPA, Drosophila Replication Protein A, HSSB, Human single stranded DNA binding protein, MST075, MSTP075, RF A, RF-A protein 1, RFA, RFA1_HUMAN, RP A, RP-A p70, RPA, RPA 70, RPA1, Replication factor A, Replication factor A protein 1, Replication protein A 70 kDa DNA-binding subunit, Replication protein A 70kDa DNA binding subunit, Replication protein A1, Replication protein A1 70kDa, Single stranded binding protein 70, Single-stranded DNA-binding protein, p70 antibody REPA1, Dmrpa1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRPA70
Short nameRPA70 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRPA70 (Antibody to)
Alternative techniqueantibodies
Identity 10289
Gene RPA1
Long gene name replication protein A1
Synonyms gene name 70kDa , replication protein A1 (70kD) replication protein A1
Synonyms REPA1 RPA70 HSSB RF-A RP-A
Locus 17p13, 3
Discovery year 1993-12-14
GenBank acession M63488
Entrez gene record 6117
Pubmed identfication 8454588
RefSeq identity NM_002945
Classification Nucleotide excision repair
Havana BLAST/BLAT OTTHUMG00000090579

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