RPA70 Antibody, Biotin Conjugated

RPA70 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, RPA70 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	RPA70
Specificity	This is a highly specific antibody against RPA70
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human RPA70
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	It can also play a role in telomere maintenance, RPA contains a conserved four cysteine-type zinc-finger motif, RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair, RPA plays an important role in DNA replication, Replication protein A (RPA), The DNA binding domain lies in the middle of RPA 70 kDa subunit and comprises two structurally homologous subdomains oriented in tandem, The RPA 70 kDa subunit binds to ssDNA and mediates interactions with many cellular and viral proteins, The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of an ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA, a highly conserved eukaryotic protein, is a heterotrimeric SSB, mitochondria, phages and viruses, recombination and repair, which mediates the transition of RPA-ssDNA interaction to a stable RPA-ssDNA complex in a redox-dependent manner, The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	REPA1 RPA70 HSSB RF-A RP-A
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	RPA70 Conjugated
Short name	Conjugated, RPA70 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, RPA70 (Antibody to)
Alternative technique	antibodies
Identity	10289
Gene	RPA1
Long gene name	replication protein A1
Synonyms gene name	70kDa , replication protein A1 (70kD) replication protein A1
Locus	17p13, 3
Discovery year	1993-12-14
GenBank acession	M63488
Entrez gene record	6117
Pubmed identfication	8454588
RefSeq identity	NM_002945
Classification	Nucleotide excision repair
Havana BLAST/BLAT	OTTHUMG00000090579

RPA70 Antibody, Biotin Conjugated

RPA70 Antibody, Biotin Conjugated size: 0.1ml 333

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