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RPE65 Antibody

RPE65 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRPE65 Primary Polyclonal Antibody
Also known asRPE65 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRPE65
SpecificityThis is a highly specific antibody against RPE65
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RPE65
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2, RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated, Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the Î, The soluble form of the protein binds vitamin A, This protein is important in 11-cis retinal production as well as in visual pigment regeneration, ², -carotene dioxygenase family, The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LCA 2, LCA2, Leber congenital amaurosis, RP 20, RP20, RPE 65, RPE65, RPE65_HUMAN, Retinal pigment epithelium specic 61 kDa protein, Retinal pigment epithelium specic 65 kDa protein, Retinal pigment epithelium specic protein, Retinal pigment epithelium specic protein 65kDa, Retinal pigment epithelium-specic 65 kDa protein, Retinitis pigmentosa 20, Retinoid isomerohydrolase, mRPE 65, mRPE65, p63, rd 12, rd12, sRPE 65, sRPE65, All-trans-retinyl-palmitate hydrolase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRPE65
Short nameRPE65 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRPE65 (Antibody to)
Alternative techniqueantibodies
Identity 10294
Gene RPE65
Long gene name RPE65, retinoid isomerohydrolase
Synonyms gene RP20
Synonyms gene name retinal pigment epithelium-specific protein 65kDa
Synonyms LCA2 rd12 BCO3
Synonyms name BCO family, member 3 retinol isomerase all-trans-retinyl-palmitate hydrolase
Locus 1p31, 3
Discovery year 1993-10-04
GenBank acession U18991
Entrez gene record 6121
Pubmed identfication 8340400 16116091
RefSeq identity NM_000329
Havana BLAST/BLAT OTTHUMG00000009208
Locus Specific Databases Mutations of the RPE65 Gene

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