Name : RPE65 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8383953780
| Long name | ALEXA FLUOR 350 Conjugated, RPE65 Polyclonal Antibody |
| Also known as | Anti-RPE65 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RPE65 |
| Specificity | This is a highly specific antibody against RPE65 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RPE65 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2, RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated, Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the Î, The soluble form of the protein binds vitamin A, This protein is important in 11-cis retinal production as well as in visual pigment regeneration, ², -carotene dioxygenase family, The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | LCA2 rd12 BCO3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | RPE65 |
| Short name | RPE65 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, RPE65 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10294 |
| Gene | RPE65 |
| Long gene name | RPE65, retinoid isomerohydrolase |
| Synonyms gene | RP20 |
| Synonyms gene name | retinal pigment epithelium-specific protein 65kDa |
| Synonyms name | BCO family, member 3 retinol isomerase all-trans-retinyl-palmitate hydrolase |
| Locus | 1p31, 3 |
| Discovery year | 1993-10-04 |
| GenBank acession | U18991 |
| Entrez gene record | 6121 |
| Pubmed identfication | 8340400 16116091 |
| RefSeq identity | NM_000329 |
| Havana BLAST/BLAT | OTTHUMG00000009208 |
| Locus Specific Databases | Mutations of the RPE65 Gene |