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RPH3AL Antibody, Cy3 Conjugated

RPH3AL Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, RPH3AL Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRPH3AL
SpecificityThis is a highly specific antibody against RPH3AL
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human RPH3AL
Gene ID number9501
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It contains one FYVE-type zinc finger and one Rab-binding (RBD) domain, It is believed to play a role regulating calcium-dependent secretory vesicle exocytosis in endocrine and exocrine cells, Rabphilin-3AL is expressed in a variety of tissues, Rabphilin-3AL knockout mice display accumulation of secretory granules and irregular shape in exocrine cells, Through an interaction with Rab 3, Via its RBD domain, With lower affinity, also known as RPH3AL or NOC2, but unlike its related protein, heart and thyroid, is a cytoplasmic Rab GTPase effector, liver, ovary, pancreas, rabphilin-3A, rabphilin-3AL can also bind Rab 3 and Rab 8 with its RBD domain, rabphilin-3AL can inhibit G-protein signaling in endocrine pancreas and positively regulate insulin secretion, rabphilin-3AL does not contain any C2 domains, rabphilin-3AL is capable of binding Rab 27a and, rabphilin-3AL is recruited to dense-core vesicles, skeletal muscle, stomach, through this interaction, with highest levels found in kidney, Rabphilin-3AL (rabphilin-3A-like)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms Noc2
Properties 1 of the RPH3AL Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRPH3AL Conjugated
Short name Conjugated, RPH3AL Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, rabphilin 3A-like (without complement component 2 domains) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, NOC2, RPH3AL and IDBG-13853 and ENSG00000181031 and 9501, RPH3AL and IDBG-632666 and ENSBTAG00000039819 and 617294, Rph3al and IDBG-200631 and ENSMUSG00000020847 and 380714, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0006887 and exocytosis and biological process this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0017137 and Rab GTPase binding and molecular function this GO :0017158 and regulation of calcium ion-dependent exocytosis and biological process this GO :0030141 and secretory granule and cellular component this GO :0030274 and LIM domain binding and molecular function this GO :0030658 and transport vesicle membrane and cellular component this GO :0030667 and secretory granule membrane and cellular component this GO :0042493 and response to drug and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050714 and positive regulation of protein secretion and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008092: cytoskeletal protein binding and also this GO :0017137: Rab GTPase binding and also this GO :0030274: LIM domain binding and also this GO :0046872: metal ion binding, this GO :0008092: cytoskeletal protein binding, this GO :0017137: Rab GTPase binding, this GO :0030274: LIM domain binding, this GO :0046872: metal ion binding, rabphilin 3A-like (without C2 domains)
Identity 10296
Gene RPH3AL
Long gene name rabphilin 3A-like (without C2 domains)
Locus 17p13, 3
Discovery year 1999-04-14
Entrez gene record 9501
Pubmed identfication 10395805
RefSeq identity NM_006987
Havana BLAST/BLAT OTTHUMG00000090273

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