| Long name | RPS6KA1(Ser352) Primary Polyclonal Antibody |
| Also known as | RPS6KA1(Ser352) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RPS6KA1 Ser352 |
| Specificity | This is a highly specific antibody against RPS6KA1 Ser352 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser352 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human RPS6KA1 around the phosphorylation site of Ser352 |
| Gene ID number | 6195 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation, Rsk2 and Rsk3, These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2, which includes Rsk1, Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 90 kDa ribosomal protein S6 kinase 1 , 90kD, EC 2, HU 1 , HU1 , KS6A1_MOUSE, MAP kinase activated protein kinase 1a , MAPKAP kinase 1A , MAPKAPK1A , MGC79981 , Mitogen-activated protein kinase-activated protein kinase 1A, RPS6K1 alpha , RPS6KA1phospho S352, RSK , RSK 1 , RSK 1 p90 , RSK1 , Ribosomal S6 kinase 1 , Ribosomal protein S6 kinase 90kD 1 , Ribosomal protein S6 kinase 90kD polypeptide 1 , Ribosomal protein S6 kinase 90kDa polypeptide 1 , Ribosomal protein S6 kinase alpha 1 , Ribosomal protein S6 kinase polypeptide 1 , Rps6ka1 , S6K alpha 1 , dJ590P13, dJ590P13, p90 RSK1 , p90S6K , p90rsk , polypeptide 1 , pp90RSK1 , rps6ka , 1 , 1 , 1 ribosomal protein S6 kinase, 7, 11, p90RSK Ser352 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RPS6KA1(Ser352) |
| Short name | RPS6KA1(Ser352) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 90kDa, polypeptide 1(Ser352) (Antibody to), ribosomal protein S6 phosphorylation catalyst |
| Alternative technique | antibodies |
| Alternative to gene target | 90kDa, HU-1 and MAPKAPK1A and RSK and RSK1, RPS6KA1 and IDBG-645125 and ENSBTAG00000014447 and 533908, RPS6KA1 and IDBG-94680 and ENSG00000117676 and 6195, Rps6ka1 and IDBG-195412 and ENSMUSG00000003644 and 20111, alcohol group as acceptor, alcohol group as acceptor and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, alcohol group as acceptor and molecular function this GO :0030307 and positive regulation of cell growth and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043555 and regulation of translation in response to stress and biological process this GO :0043620 and regulation of DNA-dependent transcription in response to stress and biological process this GO :0045087 and innate immune response and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :2000491 and positive regulation of hepatic stellate cell activation and biological process, nuclei, polypeptide 1, this GO :0000287 and magnesium ion binding and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007049 and cell cycle and biological process this GO :0007165 and signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004712: protein serine/threonine/tyrosine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004712: protein serine/threonine/tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0016773: phosphotransferase activity, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773: phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, ribosomal protein S6 kinase |
| Identity | 10430 |
| Gene | RPS6KA1 |
| Long gene name | ribosomal protein S6 kinase A1 |
| Synonyms gene name | 90kD, polypeptide 1 , ribosomal protein S6 kinase |
| Synonyms | RSK RSK1 HU-1 p90Rsk |
| Locus | 1p36, 11 |
| Discovery year | 1994-07-11 |
| GenBank acession | BC014966 |
| Entrez gene record | 6195 |
| Pubmed identfication | 8141249 |
| RefSeq identity | NM_002953 |
| Classification | Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000004003 |
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