| Long name | RPS6KB1(Ser441+Thr444) Antibody |
| Also known as | RPS6KB1(Ser441+Thr444) Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RPS6KB1 Ser441+Thr444 |
| Specificity | This is a highly specific antibody against RPS6KB1 Ser441+Thr444 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser441+Thr444 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human RPS6KB1 around the phosphorylation site of Ser441+Thr444 |
| Gene ID number | 6198 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Activity of this gene has been associated with human cancer, Alternatively spliced transcript variants have been observed, Jan 2013], The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations, There are two pseudogenes for this gene on chromosome 17, [provided by RefSeq, and cell proliferation, cell growth, This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 70 kDa ribosomal protein S6 kinase 1, 70kDa, KS6B1_HUMAN, P70 Beta1, P70S6K1, PS6K, RPS6KB1, RPS6KB1 phospho Ser441+Thr444, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1, S6K, S6K-beta-1, S6K1, STK14A, Serine/threonine-protein kinase 14A, p-RPS6KB1 Ser441+Thr444, p70 S6 Kinase, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, p70 ribosomal S6 kinase alpha, p70-S6K, p70-S6K 1, p70-alpha, p70S6K-alpha, ribosomal protein S6 kinase, RPS6KB1 phospho S441+T444 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RPS6KB1(Ser441+Thr444) |
| Short name | RPS6KB1(Ser441+Thr444) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 70kDa, polypeptide 1(Ser441+Thr444) (Antibody to), ribosomal protein S6 phosphorylation catalyst |
| Alternative technique | antibodies |
| Alternative to gene target | 70kDa, RPS6KB1 and IDBG-61938 and ENSG00000108443 and 6198, RPS6KB1 and IDBG-629797 and ENSBTAG00000016851 and 404181, Rps6kb1 and IDBG-206895 and ENSMUSG00000020516 and 72508, nuclei, p70 S6KA and p70-alpha and p70-S6K and p70(S6K)-alpha and PS6K and S6K and S6K-beta-1 and S6K1 and STK14A, polypeptide 1, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0003009 and skeletal muscle contraction and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004711 and ribosomal protein S6 kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007281 and germ cell development and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0007616 and long-term memory and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0009408 and response to heat and biological process this GO :0009611 and response to wounding and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009749 and response to glucose and biological process this GO :0009986 and cell surface and cellular component this GO :0010033 and response to organic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014878 and response to electrical stimulus involved in regulation of muscle adaptation and biological process this GO :0014911 and positive regulation of smooth muscle cell migration and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004711: ribosomal protein S6 kinase activity and also this GO :0004712: protein serine/threonine/tyrosine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004711: ribosomal protein S6 kinase activity, this GO :0004712: protein serine/threonine/tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0042277: peptide binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042277: peptide binding, transferring phosphorus-containing groups and molecular function this GO :0030054 and cell junction and cellular component this GO :0031929 and TOR signaling and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032868 and response to insulin and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0033574 and response to testosterone and biological process this GO :0033762 and response to gluca this GO n and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0042277 and peptide binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043005 and neuron projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043200 and response to amino acid and biological process this GO :0043201 and response to leucine and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0045202 and synapse and cellular component this GO :0045471 and response to ethanol and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0045948 and positive regulation of translational initiation and biological process this GO :0046324 and regulation of glucose import and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048633 and positive regulation of skeletal muscle tissue growth and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, ribosomal protein S6 kinase |
| Identity | 10436 |
| Gene | RPS6KB1 |
| Long gene name | ribosomal protein S6 kinase B1 |
| Synonyms gene | STK14A |
| Synonyms gene name | 70kD, polypeptide 1 , ribosomal protein S6 kinase |
| Synonyms | S6K1 p70(S6K)-alpha PS6K |
| Locus | 17q23, 1 |
| Discovery year | 1994-07-11 |
| GenBank acession | M60724 |
| Entrez gene record | 6198 |
| Pubmed identfication | 1922062 |
| RefSeq identity | NM_003161 |
| Havana BLAST/BLAT | OTTHUMG00000150642 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue