Name : RRM2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5345242055
| Long name | RRM2 Primary Polyclonal Antibody |
| Also known as | RRM2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RRM2 |
| Specificity | This is a highly specific antibody against RRM2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RRM2 |
| Gene ID number | 6241 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, R2, R2 expression is strictly correlated to the S-phase of the cell cycle, R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex, While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, has been shown to be responsible for the production of dNTPs in response to DNA damage, is localized to the cytoplasm, p53R2, the smaller subunit, whereas R1 remains constant throughout all phases of the cell cycle, which are inactive separately, Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | RIR2_HUMAN, RR2, RR2M, RRM2, Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, R2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RRM2 |
| Short name | RRM2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RRM2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10452 |
| Gene | RRM2 |
| Long gene name | ribonucleotide reductase regulatory subunit M2 |
| Synonyms gene name | ribonucleotide reductase M2 polypeptide |
| Locus | 2p25, 1 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 6241 |
| Havana BLAST/BLAT | OTTHUMG00000090449 |