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RRM2 Antibody, Biotin Conjugated

RRM2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, RRM2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRRM2
SpecificityThis is a highly specific antibody against RRM2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human RRM2
Gene ID number6241
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, R2, R2 expression is strictly correlated to the S-phase of the cell cycle, R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex, While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, has been shown to be responsible for the production of dNTPs in response to DNA damage, is localized to the cytoplasm, p53R2, the smaller subunit, whereas R1 remains constant throughout all phases of the cell cycle, which are inactive separately, Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRRM2 Conjugated
Short name Conjugated, RRM2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, RRM2 (Antibody to)
Alternative techniqueantibodies
Identity 10452
Gene RRM2
Long gene name ribonucleotide reductase regulatory subunit M2
Synonyms gene name ribonucleotide reductase M2 polypeptide
Locus 2p25, 1
Discovery year 2001-06-22
Entrez gene record 6241
Havana BLAST/BLAT OTTHUMG00000090449

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