Name : RSK3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2629156130
| Long name | RSK3 Primary Polyclonal Antibody |
| Also known as | RSK3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RSK3 |
| Specificity | This is a highly specific antibody against RSK3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RSK3/Ribosomal S6 kinase 3 |
| Gene ID number | 6196 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk2 and Rsk3, Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, Ser363 and Thr573, Several sites, These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, Thr359, are important for its activation, including extracellular signal-regulated protein kinases Erk1 and Erk2, phosphorylates potential nuclear targets and may have a unique upstream activator, such as Ser380, which includes Rsk1, RSK3(Ribosomal S6 kinase 3)is a member of a family of 90-kDa ribosomal protein S6 kinases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HU 2, KS6A2_HUMAN, MAP kinase activated protein kinase 1c, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, MAPKAPK1C, RPS6KA2, RSK 3, RSK-3, Ribosomal S6 kinase 3, Ribosomal protein S6 kinase alpha-2, S6K alpha, S6K alpha 2, S6K-alpha-2, p90-RSK 2, p90RSK 2, p90RSK2, pp90RSK 3, pp90RSK3, 90 kDa ribosomal protein S6 kinase 2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RSK3 |
| Short name | RSK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RSK3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10431 |
| Gene | RPS6KA2 |
| Long gene name | ribosomal protein S6 kinase A2 |
| Synonyms gene name | 90kD, polypeptide 2 , ribosomal protein S6 kinase |
| Synonyms | RSK RSK3 HU-2 |
| Locus | 6q27 |
| Discovery year | 1994-07-11 |
| GenBank acession | L07598 |
| Entrez gene record | 6196 |
| Pubmed identfication | 8141249 |
| RefSeq identity | NM_021135 |
| Classification | Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000016007 |