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RUNX2(Ser451) Antibody, Biotin Conjugated

RUNX2(Ser451) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, RUNX2(Ser451) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRUNX2 Ser451
SpecificityThis is a highly specific antibody against RUNX2 Ser451
ModificationPhosphorylation
Modification siteSer451
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RUNX2 around the phosphorylation site of Ser451
Gene ID number860
Swiss ProtQ13950
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 5'-PYGPYGGT-3', CBF binds to the core site, Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification, IL-3 and GM-CSF promoters, In osteoblasts, Inhibits KAT6B-dependent transcriptional activation, LCK, T-cell receptor enhancers, alpha 1(I) collagen, bone sialoprotein, including murine leukemia virus, of a number of enhancers and promoters, osteocalcin, osteopontin, polyomavirus enhancer, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity), Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms AML3 PEBP2A1 PEBP2aA1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRUNX2(Ser451) Conjugated
Short name Conjugated, RUNX2(Ser451) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, RUNX2(Ser451) (Antibody to)
Alternative techniqueantibodies
Identity 10472
Gene RUNX2
Long gene name runt related transcription factor 2
Synonyms gene CCD CBFA1 CCD1
Synonyms gene name runt-related transcription factor 2
Locus 6p21, 1
Discovery year 1994-11-02
GenBank acession AF001450
Entrez gene record 860
Pubmed identfication 7835892
RefSeq identity NM_004348
Havana BLAST/BLAT OTTHUMG00000014774

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