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RUNX3 Antibody

RUNX3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenRUNX3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the RUNX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis RUNX3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13761
PurityAntigen affinity
Description A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, It also interacts with other transcription factors, It functions as a tumor suppressor, Multiple transcript variants encoding different isoforms have been found for this gene, and can either activate or suppress transcription, and the gene is frequently deleted or transcriptionally silenced in cancer, This gene encodes a member of the runt domain-containing family of transcription factors
ImmunogenA portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RUNX3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetRUNX3
Short nameRUNX3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namerunt-related transcription factor 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target AML2 and CBFA3 and PEBP2aC, ATP binding, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007411 and axon guidance and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031175 and neuron projection development and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0045087 and innate immune response and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048469 and cell maturation and biological process this GO :0048935 and peripheral nervous system neuron development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, RUNX3 and IDBG-645327 and ENSBTAG00000019800 and 617389, RUNX3 and IDBG-94257 and ENSG00000020633 and 864, Runx3 and IDBG-196773 and ENSMUSG00000070691 and 12399, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0002062 and chondrocyte differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, runt-related transcription factor 3
Identity 10473
Gene RUNX3
Long gene name runt related transcription factor 3
Synonyms gene CBFA3
Synonyms gene name runt-related transcription factor 3
Synonyms AML2 PEBP2A3
Locus 1p36, 11
Discovery year 1994-11-02
GenBank acession BC013362
Entrez gene record 864
Pubmed identfication 7835892
RefSeq identity NM_004350
Havana BLAST/BLAT OTTHUMG00000003316

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