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Ryanodine Receptor Antibody

Ryanodine Receptor Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRyanodine Receptor Primary Polyclonal Antibody
Also known asRyanodine Receptor PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRyanodine Receptor
Specificity Ryanodine Receptor 2, This antibody will recognize Ryanodine Receptor 1, and Ryanodine Receptor 3, This is a highly specific antibody against Ryanodine Receptor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range4700-4750/5038
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ryanodine Receptor
Gene ID number6261, 6262, 6263
Swiss Prot Q15413, Q92736, P21817
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In non-mammalian vertebrates, Mammalian RyR isoforms are the product of three different genes: RyR-1 is expressed predominantly in skeletal muscle and areas of the brain, RyR-2 is expressed predominantly in heart muscle but also found in the stomach, RyR-3 and RyR-2 isoforms respectively, The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains, The remainder of the protein, and RyR-3 is found in smooth muscle and the brain (striatum, beta and cardiac which correlate loosely to the mammalian RyR-1, endothelial cells and diffuse areas of the brain, is located in the cytoplasm between the transverse tubule and the SR, region, termed the ", thalamus and hippocampus), the RyR isoforms are termed alpha, The Ryanodine Receptor (RyR) is the channel responsible for calcium release from muscle cell Sarcoplasmic Reticulum (SR) and also plays a role in calcium regulation in non-muscle cells, foot"
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARVC 2, ARVC2, ARVD 2, ARVD2, Brain ryanodine receptor calcium release channel, Brain type ryanodine receptor, CCO, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor calcium release channel, Cardiac muscle type ryanodine receptor, Central core disease of muscle, HBRR, MHS, MHS1, RYDR, RYR, RYR 1, RYR 2, RYR 3, RYR1, RYR2, RYR3, Ryanodine receptor 1, Ryanodine receptor 1 skeletal, Ryanodine receptor 2, Ryanodine receptor 2 cardiac, Ryanodine receptor 3, Ryanodine receptor type1, SKRR, Sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle type ryanodine receptor, Type 1 like ryanodine receptor, VTSIP, hRYR 2, hRYR2, Arrhythmogenic right ventricular dysplasia 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRyanodine Receptor
Short nameRyanodine Receptor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRyanodine Receptor (Antibody to)
Alternative techniqueantibodies
Identity 10485
Gene RYR3
Long gene name ryanodine receptor 3
Locus 15q13, 3-q14
Discovery year 1993-05-12
Entrez gene record 6263
Pubmed identfication 8276408
Classification Ryanodine receptors EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000172253

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