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Ryanodine Receptor Antibody, ALEXA FLUOR 488

Ryanodine Receptor Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Ryanodine Receptor Polyclonal Antibody
Also known asAnti-Ryanodine Receptor PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRyanodine Receptor
SpecificityThis is a highly specific antibody against Ryanodine Receptor
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range4700-4750/5038
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ryanodine Receptor
Gene ID Number6261, 6262, 6263
Swiss Prot Q15413, Q92736, P21817
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen In non-mammalian vertebrates, Mammalian RyR isoforms are the product of three different genes: RyR-1 is expressed predominantly in skeletal muscle and areas of the brain, RyR-2 is expressed predominantly in heart muscle but also found in the stomach, RyR-3 and RyR-2 isoforms respectively, The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains, The remainder of the protein, and RyR-3 is found in smooth muscle and the brain (striatum, beta and cardiac which correlate loosely to the mammalian RyR-1, endothelial cells and diffuse areas of the brain, is located in the cytoplasm between the transverse tubule and the SR, region, termed the ", thalamus and hippocampus), the RyR isoforms are termed alpha, The Ryanodine Receptor (RyR) is the channel responsible for calcium release from muscle cell Sarcoplasmic Reticulum (SR) and also plays a role in calcium regulation in non-muscle cells, foot"
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Ryanodine Receptor Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetRyanodine Receptor
Short nameRyanodine Receptor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Ryanodine Receptor (Antibody to)
Alternative techniqueantibodies
Identity 10485
Gene RYR3
Long gene name ryanodine receptor 3
Locus 15q13, 3-q14
Discovery year 1993-05-12
Entrez gene record 6263
Pubmed identfication 8276408
Classification Ryanodine receptors EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000172253

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