Name : RYK (1671CT575.42.61) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN2085877157
| Long name | 42, 61) Monoclonal Antibody, RYK (1671CT575 |
| Also known as | 42, 61) Monoclonal Antibody, RYK (1671CT575 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RYK |
| Specificity | This is a highly specific antibody against RYK |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1671CT575, 42, 61 |
| Source | This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK |
| Gene ID number | 6259 |
| Swiss Prot | P34925 |
| Tested Applications | FCM, WB |
| Recommended dilutions | WB(1:1000), FC(1:25) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In response to WNT3 stimulation, Involved in neuron differentiation, WNT3, WNT3A and WNT5A, axon guidance, corpus callosum establishment and neurite outgrowth, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development, such as WNT1, May be a coreceptor along with FZD8 of Wnt proteins |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | D3S3195, JTK5A, RYK, RYK1, Tyrosine-protein kinase RYK, JTK5 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 42, 61) Monoclonal, RYK (1671CT575 |
| Short name | 42, 61) Monoclonal Antibody, RYK (1671CT575 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 42, 61) monoclonal (Antibody to), receptor-like tyrosine kinase (1671CT575 |
| Alternative technique | antibodies |
| Alternative to gene target | D3S3195 and JTK5 and JTK5A and RYK1, RYK and IDBG-57467 and ENSG00000163785 and 6259, RYK and IDBG-638818 and ENSBTAG00000016999 and 781353, Ryk and IDBG-194079 and ENSMUSG00000032547 and 20187, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007409 and axonogenesis and biological process this GO :0007411 and axon guidance and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005109: frizzled binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005109: frizzled binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0017147: Wnt-protein binding, this GO :0042813: Wnt-activated receptor activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017147: Wnt-protein binding and also this GO :0042813: Wnt-activated receptor activity, transferring phosphorus-containing groups and molecular function this GO :0017147 and Wnt-protein binding and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0022038 and corpus callosum development and biological process this GO :0030182 and neuron differentiation and biological process this GO :0031175 and neuron projection development and biological process this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048843 and negative regulation of axon extension involved in axon guidance and biological process this GO :0050919 and negative chemotaxis and biological process this GO :0071679 and commissural neuron axon guidance and biological process, receptor-like tyrosine kinase |
| Identity | 10481 |
| Gene | RYK |
| Long gene name | receptor-like tyrosine kinase |
| Synonyms gene | JTK5A |
| Synonyms gene name | JTK5A protein tyrosine kinase RYK receptor-like tyrosine kinase |
| Synonyms | D3S3195 RYK1 JTK5 |
| Locus | 3q22, 2 |
| Discovery year | 1993-09-28 |
| GenBank acession | S59184 |
| Entrez gene record | 6259 |
| Pubmed identfication | 8386829 |
| RefSeq identity | NM_001005861 |
| Classification | Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000159750 |