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S100A8 Antibody / MRP8

S100A8 Antibody / MRP8 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenS100A8 / MRP8
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the S100A8 antibody should be determined by the researcher
Intented useThis S100A8 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P27005
PurityAntigen affinity
Description Altered expression of this protein is associated with the disease cystic fibrosis, It is also known as Calgranulin A, MRP8 and Calprotectin L1L subunit, S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs, This protein may function in the inhibition of casein kinase and as a cytokine, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation, S100 calcium-binding protein A8 is a protein that in humans is encoded by the S100A8 gene
ImmunogenAmino acids 2-89 of mouse MRP8/S100A8 were used as the immunogen for the S100A8 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the S100A8 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetS100A8 / MRP8
Short nameS100A8 Antibody / MRP8
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameS100 calcium binding protein A8 (Antibody to) / MRP8
Alternative techniqueantibodies
Alternative to gene target 60B8AG and CAGA and CFAG and CGLA and CP-10 and L1Ag and MA387 and MIF and MRP8 and NIF and P8, RAGE receptor binding, S100A8 and IDBG-102654 and ENSG00000143546 and 6279, S100A8 and IDBG-632868 and ENSBTAG00000012640 and 616818, S100a8 and IDBG-168077 and ENSMUSG00000056054 and 20201, nuclei, this GO :0001816 and cytokine production and biological process this GO :0002523 and leukocyte migration involved in inflammatory response and biological process this GO :0002526 and acute inflammatory response and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006914 and autophagy and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0008017 and microtubule binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0010043 and response to zinc ion and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0032119 and sequestering of zinc ion and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032602 and chemokine production and biological process this GO :0035662 and Toll-like receptor 4 binding and molecular function this GO :0042060 and wound healing and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0050544 and arachidonic acid binding and molecular function this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050786 and RAGE receptor binding and molecular function this GO :0050832 and defense response to fungus and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070488 and neutrophil aggregation and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008017: microtubule binding and also this GO :0008270: zinc ion binding and also this GO :0035662: Toll-like receptor 4 binding and also this GO :0050544: arachidonic acid binding and also this GO :0050786: RAGE receptor binding, this GO :0005515: protein binding, this GO :0008017: microtubule binding, this GO :0008270: zinc ion binding, this GO :0035662: Toll-like receptor 4 binding, this GO :0050544: arachidonic acid binding, this GO :0050786: RAGE receptor binding, S100 calcium binding protein A8
Identity 10498
Gene S100A8
Long gene name S100 calcium binding protein A8
Synonyms gene CAGA CFAG
Synonyms gene name S100 calcium-binding protein A8 (calgranulin A) S100 calcium binding protein A8 (calgranulin A)
Synonyms P8 MRP8 60B8AG CGLA
Locus 1q21, 3
Discovery year 1989-05-19
GenBank acession BC005928
Entrez gene record 6279
RefSeq identity NM_002964
Classification S100 calcium binding proteins EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000013124

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