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S1P1 Antibody

S1P1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameS1P1 Primary Polyclonal Antibody
Also known asS1P1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenS1P1
SpecificityThis is a highly specific antibody against S1P1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range106-146/382
Subcellular location Helical, Extracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human S1P1
Gene ID number1901
Swiss ProtP21453
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development, PTK2/FAK1 and MAP kinases, Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury, Plays a role in the migration of osteoclast precursor cells, Plays an important role in cell migration, Plays an important role in the regulation of sprouting angiogenesis and vascular maturation, Required for normal chemotaxis toward sphingosine 1-phosphate, Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs, Required for normal embryonic heart development and normal cardiac morphogenesis, SRC, Signaling leads to the activation of RAC1, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1, the regulation of bone mineralization and bone homeostasis (By similarity), G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD363, CHEDG1, D1S3362, ECGF1, EDG-1, Endothelial differentiation G-protein coupled receptor 1, S1P receptor 1, S1P receptor Edg-1, S1P1, S1PR1, Sphingosine 1-phosphate receptor 1, Sphingosine 1-phosphate receptor Edg-1, EDG1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetS1P1
Short nameS1P1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameS1P1 (Antibody to)
Alternative techniqueantibodies

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