Name : S1P1 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN6006701650
| Long name | Cy7 Conjugated, S1P1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | S1P1 |
| Specificity | This is a highly specific antibody against S1P1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 106-146/382 |
| Subcellular location | Helical, Extracellular |
| Source | KLH conjugated synthetic peptide derived from human S1P1 |
| Gene ID number | 1901 |
| Swiss Prot | P21453 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development, PTK2/FAK1 and MAP kinases, Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury, Plays a role in the migration of osteoclast precursor cells, Plays an important role in cell migration, Plays an important role in the regulation of sprouting angiogenesis and vascular maturation, Required for normal chemotaxis toward sphingosine 1-phosphate, Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs, Required for normal embryonic heart development and normal cardiac morphogenesis, SRC, Signaling leads to the activation of RAC1, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1, the regulation of bone mineralization and bone homeostasis (By similarity), G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | CD363, CHEDG1, D1S3362, ECGF1, EDG-1, Endothelial differentiation G-protein coupled receptor 1, S1P receptor 1, S1P receptor Edg-1, S1P1, S1PR1, Sphingosine 1-phosphate receptor 1, Sphingosine 1-phosphate receptor Edg-1, EDG1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | S1P1 Conjugated |
| Short name | Conjugated, S1P1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, S1P1 (Antibody to) |
| Alternative technique | antibodies |