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SAMHD1 Antibody, Cy5.5 Conjugated

SAMHD1 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, SAMHD1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSAMHD1
SpecificityThis is a highly specific antibody against SAMHD1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SAMHD1
Gene ID number4861
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A form of Aicardi-Goutieres syndrome, Clinical features as thrombocytopenia, Death often occurs in early childhood, May play a role in mediating proinflammatory responses to TNF-alpha signaling, No expression is seen in brain and thymus, Severe neurological dysfunctions manifest in infancy as progressive microcephaly, a genetically heterogeneous disease characterized by cerebral atrophy, and negative serologic investigations for common prenatal infection, chronic cerebrospinal fluid (CSF) lymphocytosis, dystonic posturing and profound psychomotor retardation, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process, increased CSF alpha-interferon, intracranial calcifications, leukoencephalopathy, liver, lung and peripheral blood leukocytes, placenta, skeletal muscle, small intestine, spasticity, spleen, Involvement in disease:Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) , Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response, Tissue specificity:Expressed in heart
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms SBBI88 Mg11 HDDC1 MOP-5 AGS5
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetSAMHD1 Conjugated
Short name Conjugated, SAMHD1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, SAMHD1 (Antibody to)
Alternative techniqueantibodies
Identity 15925
Gene SAMHD1
Long gene name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Synonyms gene name SAM domain and HD domain 1
Synonyms name HD domain containing 1 monocyte protein 5 Aicardi-Goutieres syndrome 5
Locus 20q11, 23
Discovery year 2001-07-31
GenBank acession AF228421
Entrez gene record 25939
Pubmed identfication 11064105 11230166 22056990
RefSeq identity NM_015474
Classification Sterile alpha motif domain containing
Havana BLAST/BLAT OTTHUMG00000032402
Locus Specific Databases LRG_281

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