| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | SAP97 / DLG1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the SAP97 antibody should be determined by the researcher |
| Intented use | This SAP97 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q12959 |
| Purity | Antigen affinity |
| Description | In the brain, Mice in which the SAP97 gene has been knocked out die perinatally, Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength, SAP97 is expressed throughout the body in epithelial cells, SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane, There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, also known as synapse-associated protein 97 or SAP97, and deficiencies in renal function, and may interact with HPV, have a cleft palate, including the kidney and brain, is a protein that in humans is encoded by the SAP97 gene, Disks large homolog 1 (DLG1) |
| Immunogen | Amino acids 1-165 of human SAP97 were used as the immunogen for the SAP97 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SAP97 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | membrane, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | SAP97 / DLG1 |
| Short name | SAP97 Antibody / DLG1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | large homolog 1 (Drosophila), SAP97 (Antibody to) / discs |
| Alternative technique | antibodies |
| Alternative to gene target | DLG1 and IDBG-634119 and ENSBTAG00000020378 and, DLG1 and IDBG-71508 and ENSG00000075711 and 1739, Dlg1 and IDBG-152959 and ENSMUSG00000022770 and 13383, L27 domain binding, dJ1061C18, large homolog 1 (Drosophila), nuclei, this GO :0001657 and ureteric bud development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0001772 and immunological synapse and cellular component this GO :0001935 and endothelial cell proliferation and biological process this GO :0002088 and lens development in camera-type eye and biological process this GO :0002369 and T cell cytokine production and biological process this GO :0004385 and guanylate kinase activity and molecular function this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005605 and basal lamina and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0007015 and actin filament organization and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process this GO :0007163 and establishment or maintenance of cell polarity and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0008104 and protein localization and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0014069 and postsynaptic density and cellular component this GO :0014704 and intercalated disc and cellular component this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016032 and viral process and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0019902 and phosphatase binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030432 and peristalsis and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031434 and mitogen-activated protein kinase kinase binding and molecular function this GO :0031579 and membrane raft organization and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0031641 and regulation of myelination and biological process this GO :0032147 and activation of protein kinase activity and biological process this GO :0032947 and protein complex scaffold and molecular function this GO :0033268 and node of Ranvier and cellular component this GO :0035748 and myelin sheath abaxonal region and cellular component this GO :0042110 and T cell activation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0042391 and regulation of membrane potential and biological process this GO :0042982 and amyloid precursor protein metabolic process and biological process this GO :0043219 and lateral loop and cellular component this GO :0043268 and positive regulation of potassium ion transport and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045121 and membrane raft and cellular component this GO :0045202 and synapse and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046939 and nucleotide phosphorylation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048608 and reproductive structure development and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0048729 and tissue morphogenesis and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060022 and hard palate development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process this GO :0097016 and L27 domain binding and molecular function this GO :0097025 and MPP7-DLG1-LIN7 complex and cellular component this GO :1902305 and regulation of sodium ion transmembrane transport and biological process, this GO :0004385: guanylate kinase activity, this GO :0004385: guanylate kinase activity and also this GO :0004721: phosphoprotein phosphatase activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0008092: cytoskeletal protein binding and also this GO :0015459: potassium channel regulator activity and also this GO :0019901: protein kinase binding and also this GO :0019902: phosphatase binding and also this GO :0031434: mitogen-activated protein kinase kinase binding and also this GO :0032947: protein complex scaffold and also this GO :0044325: ion channel binding and also this GO :0097016: L27 domain binding, this GO :0004721: phosphoprotein phosphatase activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0008092: cytoskeletal protein binding, this GO :0015459: potassium channel regulator activity, this GO :0019901: protein kinase binding, this GO :0019902: phosphatase binding, this GO :0031434: mitogen-activated protein kinase kinase binding, this GO :0032947: protein complex scaffold, this GO :0044325: ion channel binding, this GO :0097016: L27 domain binding, 1, 1 and DLGH1 and hdlg and SAP-97 and SAP97, discs |
| Identity | 2900 |
| Gene | DLG1 |
| Long gene name | discs large MAGUK scaffold protein 1 |
| Synonyms gene name | discs, large homolog 1 (Drosophila) discs large homolog 1, scribble cell polarity complex component |
| Synonyms | SAP97 SAP-97 hdlg DLGH1 dJ1061C18, 1, 1 |
| Synonyms name | discs large homolog 1 presynaptic protein SAP97 synapse-associated protein 97 |
| Locus | 3q29 |
| Discovery year | 1995-05-04 |
| GenBank acession | U13897 |
| Entrez gene record | 1739 |
| Pubmed identfication | 7937897 8825652 |
| RefSeq identity | NM_004087 |
| Classification | Scribble complex Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000047972 |
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