Name : SASS6 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9875586680
| Long name | SASS6 Primary Polyclonal Antibody |
| Also known as | SASS6 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SASS6 |
| Specificity | This is a highly specific antibody against SASS6 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SASS6 |
| Gene ID number | 163786 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6, Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole, LK4, SAS-6, SAS-6 associates only transiently with nascent procentrioles, SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain, SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation, SAS-6 levels oscillate during the cell cycle, The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation, and it accumulates again at the end of the following G1 phase, it is degraded in mitosis starting at anaphase, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles, SAS-6 (spindle assembly abnormal protein 6 homolog |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HsSAS6, MGC119440, PJA2_HUMAN, SAS 6, SAS6, SASS 6, Spindle assembly 6 homolog, Spindle assembly 6 homolog C, Spindle assembly abnormal protein 6 homolog, elegans, HsSAS 6 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SASS6 |
| Short name | SASS6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SASS6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25403 |
| Gene | SASS6 |
| Long gene name | SAS-6 centriolar assembly protein |
| Synonyms gene name | elegans) , spindle assembly 6 homolog (C |
| Synonyms | DKFZp761A078 SAS-6 FLJ22097 SAS6 |
| Locus | 1p21, 2 |
| Discovery year | 2005-10-13 |
| GenBank acession | AL834265 |
| Entrez gene record | 163786 |
| Pubmed identfication | 15665853 14654843 |
| RefSeq identity | NM_194292 |
| Havana BLAST/BLAT | OTTHUMG00000010754 |