Name : Scavenger Receptor BII Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1474735906
| Long name | Scavenger Receptor BII Antibody |
| Also known as | Scavenger Receptor BII Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Scavenger Receptor BII |
| Specificity | This is a highly specific antibody against Scavenger Receptor BII |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 222-242/478 |
| Subcellular location | Helical |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Scavenger Receptor BII |
| Gene ID number | 950 |
| Swiss Prot | Q14108 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Although the role of these scavenger receptors is not completely clear, Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, SR-BI and SR-BII (previously known as SR-BI, SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues, SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells, Therefore, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells, 2) are the alternatively spliced products of a single gene, High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 85 kDa lysosomal membrane sialoglycoprotein, CD36, CD36 antigen-like 2, CD36L2, EPM4, HLGP85, LGP85, LIMP II, LIMP-2, LIMP2, LIMPII, Lysosome membrane protein 2, Lysosome membrane protein II, SCARB2, SR-BII, Scavenger receptor class B member 2, AMRF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Scavenger Receptor BII |
| Short name | Scavenger Receptor BII Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Scavenger Receptor BII (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1392 |
| Gene | CACNA1E |
| Long gene name | calcium voltage-gated channel subunit alpha1 E |
| Synonyms gene | CACNL1A6 |
| Synonyms gene name | R type, alpha 1E subunit calcium voltage-gated channel subunit alpha1 subunit E , calcium channel, voltage-dependent |
| Synonyms | Cav2, 3 BII CACH6 |
| Locus | 1q25, 3 |
| Discovery year | 1994-12-20 |
| GenBank acession | AK096563 |
| Entrez gene record | 777 |
| Pubmed identfication | 8388125 16382099 |
| RefSeq identity | NM_000721 |
| Classification | Calcium voltage-gated channel subunits EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000037301 |