| Long name | SCF Primary Polyclonal Antibody |
| Also known as | SCF PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SCF |
| Specificity | This is a highly specific antibody against SCF |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 160-210/273 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCF |
| Gene ID number | 4254 |
| Swiss Prot | P21583 |
| Tested Applications | FCM, IF(IHC-F), IF(IHC-P), IHC-F, IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | KITLG/SCF acts synergistically with other cytokines, KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, KITLG/SCF and KIT promote activation of PLCG1, KITLG/SCF and KIT promote activation of STAT family members STAT1, KITLG/SCF binding can activate several signaling pathways, Plays an essential role in the regulation of cell survival and proliferation, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, STAT3 and STAT5, and in melanogenesis, and subsequent activation of the kinase AKT1, gametogenesis, hematopoiesis, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, mast cell development, migration and function, probably interleukins, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Ligand for the receptor-type protein-tyrosine kinase KIT |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FPH2, KITLG, KL-1, Kit ligand, Kitl, MGF, Mast cell growth factor, SCF, SHEP7, Stem cell factor, c-Kit ligand, SF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SCF |
| Short name | SCF Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SCF (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6343 |
| Gene | KITLG |
| Long gene name | KIT ligand |
| Synonyms gene | MGF |
| Synonyms | SCF SF Kitl KL-1 FPH2 |
| Synonyms name | mast cell growth factor stem cell factor steel factor familial progressive hyperpigmentation 2 |
| Locus | 12q21, 32 |
| Discovery year | 1991-06-04 |
| GenBank acession | M59964 |
| Entrez gene record | 4254 |
| Pubmed identfication | 2208279 1707188 19375057 |
| RefSeq identity | NM_003994 |
| Havana BLAST/BLAT | OTTHUMG00000169888 |
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