Name : SCF Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8028144356
| Long name | Biotin Conjugated, SCF Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SCF |
| Specificity | This is a highly specific antibody against SCF |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 160-210/273 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human SCF |
| Gene ID number | 4254 |
| Swiss Prot | P21583 |
| Tested applications | IHC-F, IHC-P, WB |
| Recommended dilutions | IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | KITLG/SCF acts synergistically with other cytokines, KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, KITLG/SCF and KIT promote activation of PLCG1, KITLG/SCF and KIT promote activation of STAT family members STAT1, KITLG/SCF binding can activate several signaling pathways, Plays an essential role in the regulation of cell survival and proliferation, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, STAT3 and STAT5, and in melanogenesis, and subsequent activation of the kinase AKT1, gametogenesis, hematopoiesis, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, mast cell development, migration and function, probably interleukins, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Ligand for the receptor-type protein-tyrosine kinase KIT |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | SCF SF Kitl KL-1 FPH2 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SCF Conjugated |
| Short name | Conjugated, SCF Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, SCF (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6343 |
| Gene | KITLG |
| Long gene name | KIT ligand |
| Synonyms gene | MGF |
| Synonyms name | mast cell growth factor stem cell factor steel factor familial progressive hyperpigmentation 2 |
| Locus | 12q21, 32 |
| Discovery year | 1991-06-04 |
| GenBank acession | M59964 |
| Entrez gene record | 4254 |
| Pubmed identfication | 2208279 1707188 19375057 |
| RefSeq identity | NM_003994 |
| Havana BLAST/BLAT | OTTHUMG00000169888 |