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SCF Antibody, Biotin Conjugated

SCF Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, SCF Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSCF
SpecificityThis is a highly specific antibody against SCF
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range160-210/273
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SCF
Gene ID number4254
Swiss ProtP21583
Tested applications IHC-F, IHC-P, WB
Recommended dilutions IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background KITLG/SCF acts synergistically with other cytokines, KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, KITLG/SCF and KIT promote activation of PLCG1, KITLG/SCF and KIT promote activation of STAT family members STAT1, KITLG/SCF binding can activate several signaling pathways, Plays an essential role in the regulation of cell survival and proliferation, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, STAT3 and STAT5, and in melanogenesis, and subsequent activation of the kinase AKT1, gametogenesis, hematopoiesis, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, mast cell development, migration and function, probably interleukins, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Ligand for the receptor-type protein-tyrosine kinase KIT
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms SCF SF Kitl KL-1 FPH2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSCF Conjugated
Short name Conjugated, SCF Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SCF (Antibody to)
Alternative techniqueantibodies
Identity 6343
Gene KITLG
Long gene name KIT ligand
Synonyms gene MGF
Synonyms name mast cell growth factor stem cell factor steel factor familial progressive hyperpigmentation 2
Locus 12q21, 32
Discovery year 1991-06-04
GenBank acession M59964
Entrez gene record 4254
Pubmed identfication 2208279 1707188 19375057
RefSeq identity NM_003994
Havana BLAST/BLAT OTTHUMG00000169888

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