Name : SCF Antibody (KITLG)
Supplier : NJS POLY
Price :199
SKU : GEN5671070041
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | SCF (KITLG) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IF, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the SCF antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This SCF antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P21583 |
| Purity | Purified |
| Description | In adults, This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, all believed to reflect a role in cell migration, and hematopoiesis, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis, KITLG is the ligand of the tyrosine-kinase receptor encoded by the KIT locus |
| Immunogen | A portion of amino acids 244-273 from the human protein was used as the immunogen for this SCF antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SCF antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | SCF (KITLG) |
| Short name | SCF Antibody (KITLG) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SCF (Antibody to) (reagent ligand) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, FPH2 and Kitl and KL-1 and MGF and SCF and SF and SHEP7, KITLG and IDBG-50398 and ENSG00000049130 and 4254, KITLG and IDBG-630711 and ENSBTAG00000017549 and 281885, Kitl and IDBG-187862 and ENSMUSG00000019966 and 17311, growth factor activity, this GO :0001755 and neural crest cell migration and biological process this GO :0002763 and positive regulation of myeloid leukocyte differentiation and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005173 and stem cell factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008584 and male this GO nad development and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0033026 and negative regulation of mast cell apoptotic process and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0035234 and ectopic germ cell programmed cell death and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045636 and positive regulation of melanocyte differentiation and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0046579 and positive regulation of Ras protein signal transduction and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0070668 and positive regulation of mast cell proliferation and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005173: stem cell factor receptor binding and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity, this GO :0005173: stem cell factor receptor binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, KIT ligand |
| Identity | 6343 |
| Gene | KITLG |
| Long gene name | KIT ligand |
| Synonyms gene | MGF |
| Synonyms | SCF SF Kitl KL-1 FPH2 |
| Synonyms name | mast cell growth factor stem cell factor steel factor familial progressive hyperpigmentation 2 |
| Locus | 12q21, 32 |
| Discovery year | 1991-06-04 |
| GenBank acession | M59964 |
| Entrez gene record | 4254 |
| Pubmed identfication | 2208279 1707188 19375057 |
| RefSeq identity | NM_003994 |
| Havana BLAST/BLAT | OTTHUMG00000169888 |