Name : SCN2B Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1321437196
| Long name | Biotin Conjugated, SCN2B Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SCN2B |
| Specificity | This is a highly specific antibody against SCN2B |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human SCN2B |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | During the propagation of an action potential, Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23, Na+ CP type II beta(sodium channel, also known as SCN2B, beta), is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier, sodium channels allow an influx of sodium ions, type II, voltage-gated, which rapidly depolarizes the cell, 2, 3 and mouse chromosome 9 A5, Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SCN2B Conjugated |
| Short name | Conjugated, SCN2B Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, SCN2B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10589 |
| Gene | SCN2B |
| Long gene name | sodium voltage-gated channel beta subunit 2 |
| Synonyms gene name | beta polypeptide sodium channel, beta sodium channel, beta subunit sodium channel, sodium channel, type II, type II, type II, type II beta subunit , voltage gated, voltage-gated, voltage-gated, voltage-gated |
| Locus | 11q23, 3 |
| Discovery year | 1988-11-28 |
| GenBank acession | AY358945 |
| Entrez gene record | 6327 |
| Pubmed identfication | 10198179 |
| RefSeq identity | NM_004588 |
| Classification | Sodium voltage-gated channel beta subunits V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000048248 |