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SCN2B Antibody, FITC Conjugated

SCN2B Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, SCN2B Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSCN2B
SpecificityThis is a highly specific antibody against SCN2B
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SCN2B
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background During the propagation of an action potential, Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23, Na+ CP type II beta(sodium channel, also known as SCN2B, beta), is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier, sodium channels allow an influx of sodium ions, type II, voltage-gated, which rapidly depolarizes the cell, 2, 3 and mouse chromosome 9 A5, Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSCN2B Conjugated
Short name FITC Conjugated, SCN2B Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SCN2B (Antibody to)
Alternative techniqueantibodies
Identity 10589
Gene SCN2B
Long gene name sodium voltage-gated channel beta subunit 2
Synonyms gene name beta polypeptide sodium channel, beta sodium channel, beta subunit sodium channel, sodium channel, type II, type II, type II, type II beta subunit , voltage gated, voltage-gated, voltage-gated, voltage-gated
Locus 11q23, 3
Discovery year 1988-11-28
GenBank acession AY358945
Entrez gene record 6327
Pubmed identfication 10198179
RefSeq identity NM_004588
Classification Sodium voltage-gated channel beta subunits V-set domain containing
Havana BLAST/BLAT OTTHUMG00000048248

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