Name : SCRO Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7198336759
| Long name | SCRO Primary Polyclonal Antibody |
| Also known as | SCRO PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SCRO |
| Specificity | This is a highly specific antibody against SCRO |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1 |
| Gene ID number | 54165 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts also as an oncogene facilitating malignant transformation and carcinogenic progression, Defects in DCUN1D1 may be a cause of squamous cell carcinomas, Forms part of an E3 ubiquitin ligase complex for neddylation, Functions to recruit the NEDD8-charged E2 enzyme to the cullin component, Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity, Not overexpressed in aggressive adrenocortical carcinomas, Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation, and malignant tissues of squamous cell carcinoma of the oral tongue, bronchioloalveolar carcinomas, DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin, Strongly overexpressed in thyroid tumors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DCN1 like protein 1, DCUN1 domain containing protein 1, DCUN1L1, Defective in cullin neddylation protein 1 like protein 1, RP 42, RP42, RP42 homolog, SCCRO, SCRO, Squamous cell carcinoma related oncogene, Tes 3, Tes3, DCN1 defective in cullin neddylation 1 domain containing 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SCRO |
| Short name | SCRO Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SCRO (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18184 |
| Gene | DCUN1D1 |
| Long gene name | defective in cullin neddylation 1 domain containing 1 |
| Synonyms gene name | DCN1, cerevisiae) , defective in cullin neddylation 1, domain containing 1 (S |
| Synonyms | RP42 SCRO DCUN1L1 Tes3 SCCRO |
| Synonyms name | squamous cell carcinoma related oncogene |
| Locus | 3q26, 33 |
| Discovery year | 2005-07-11 |
| GenBank acession | AF292100 AK056335 |
| Entrez gene record | 54165 |
| Pubmed identfication | 10777668 15988528 |
| RefSeq identity | NM_020640 |
| Havana BLAST/BLAT | OTTHUMG00000158314 |