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SCRO Antibody, Biotin Conjugated

SCRO Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SCRO Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSCRO
SpecificityThis is a highly specific antibody against SCRO
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SCRO/DCUN1D1
Gene ID number54165
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts also as an oncogene facilitating malignant transformation and carcinogenic progression, Defects in DCUN1D1 may be a cause of squamous cell carcinomas, Forms part of an E3 ubiquitin ligase complex for neddylation, Functions to recruit the NEDD8-charged E2 enzyme to the cullin component, Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity, Not overexpressed in aggressive adrenocortical carcinomas, Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation, and malignant tissues of squamous cell carcinoma of the oral tongue, bronchioloalveolar carcinomas, DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin, Strongly overexpressed in thyroid tumors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms RP42 SCRO DCUN1L1 Tes3 SCCRO
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSCRO Conjugated
Short name Conjugated, SCRO Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SCRO (Antibody to)
Alternative techniqueantibodies
Identity 18184
Gene DCUN1D1
Long gene name defective in cullin neddylation 1 domain containing 1
Synonyms gene name DCN1, cerevisiae) , defective in cullin neddylation 1, domain containing 1 (S
Synonyms name squamous cell carcinoma related oncogene
Locus 3q26, 33
Discovery year 2005-07-11
GenBank acession AF292100 AK056335
Entrez gene record 54165
Pubmed identfication 10777668 15988528
RefSeq identity NM_020640
Havana BLAST/BLAT OTTHUMG00000158314

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