| Long name | SEMA4D Primary Polyclonal Antibody |
| Also known as | SEMA4D PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SEMA4D |
| Specificity | This is a highly specific antibody against SEMA4D |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 80-130/862 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SEMA4D |
| Gene ID number | 10507 |
| Swiss Prot | Q92854 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Interaction with PLXNB1 mediates activation of RHOA, Plays a role in the immune system, Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system, Promotes signaling via SRC and PTK2B/PYK2, Promotes the migration of cerebellar granule cells and of endothelial cells, Regulates dendrite and axon branching and morphogenesis, induces B-cells to aggregate and improves their viability (in vitro), which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade, Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | A8, BB18, C9orf164, GR3, M-sema-G, SEMA4D, SEMAJ, Semaphorin-4D, coll-4, CD100 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SEMA4D |
| Short name | SEMA4D Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | (semaphorin) 4D (Antibody to), immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Alternative technique | antibodies |
| Alternative to gene target | (semaphorin) 4D, C9orf164 and CD100 and coll-4 and M-sema-G and SEMAJ, Extracellular, SEMA4D and IDBG-637043 and ENSBTAG00000001941 and 785942, SEMA4D and IDBG-75424 and ENSG00000187764 and 10507, Sema4d and IDBG-152500 and ENSMUSG00000021451 and 20354, immunoglobulin domain (Ig), semaphorin receptor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007411 and axon guidance and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0010693 and negative regulation of alkaline phosphatase activity and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0030215 and semaphorin receptor binding and molecular function this GO :0030335 and positive regulation of cell migration and biological process this GO :0031344 and regulation of cell projection organization and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043931 and ossification involved in bone maturation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0048672 and positive regulation of collateral sprouting and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050732 and negative regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0070486 and leukocyte aggregation and biological process this GO :0071526 and semaphorin-plexin signaling pathway and biological process this GO :1900220 and semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0030215: semaphorin receptor binding, this GO :0004888: transmembrane signaling receptor activity, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0030215: semaphorin receptor binding, transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Identity | 10732 |
| Gene | SEMA4D |
| Long gene name | semaphorin 4D |
| Synonyms gene | SEMAJ C9orf164 |
| Synonyms gene name | (semaphorin) 4D , chromosome 9 open reading frame 164 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain |
| Synonyms | CD100 coll-4 FLJ39737 |
| Synonyms name | M-sema G |
| Locus | 9q22, 2 |
| Discovery year | 1999-06-25 |
| GenBank acession | U60800 |
| Entrez gene record | 10507 |
| Pubmed identfication | 8876214 8969198 |
| RefSeq identity | NM_006378 |
| Classification | CD molecules Semaphorins Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000020185 |
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