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SEMCAP3 Antibody, ALEXA FLUOR 555

SEMCAP3 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, SEMCAP3 Polyclonal Antibody
Also known asAnti-SEMCAP3 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSEMCAP3
SpecificityThis is a highly specific antibody against SEMCAP3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SEMCAP3/LNX3
Gene ID Number23024
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Both the differentiation of C2C12 mouse skeletal myoblasts into myotubes and injury-induced muscle regeneration in vivo were found to be accompanied by up-regulation of PDZRN3, Depletion of PDZRN3 by RNA interference inhibited the formation of myotubes as well as the associated up-regulation of myosin heavy chain in C2C12 cells, However, It was identified in silico as a homolog of the protein known as LNX1 or SEMCAP1, Our data suggest that PDZRN3 plays an essential role in the differentiation of myoblasts into myotubes by acting either downstream or independently of myogenin, PDZRN3 itself has not previously been characterized, The PDZRN3 gene was shown to be expressed in various human tissues including the heart, The differentiation-associated increase in the expression of PDZRN3 in C2C12 cells follows that of myogenin and precedes that of myosin heavy chain, We have now evaluated the properties and functions of PDZRN3, skeletal muscle and liver and its expression in mouse skeletal muscle was developmentally regulated, two PDZ domains in its central region and a consensus-binding motif for PDZ domains at its C-terminus, which possesses ubiquitin ligase activity and binds the membrane protein Semaphorin 4C, PDZRN3 contains a RING-finger motif in its N-terminal region
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms LNX3, PDZ domain containing ring finger 3, PZRN3_HUMAN, Protein SEMACAP3, SEMACAP3, Semaphorin cytoplasmic domain associated protein, likely ortholog of mouse semaF cytoplasmic domain associated protein 3, Ligand of Numb protein X 3
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetSEMCAP3
Short nameSEMCAP3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, SEMCAP3 (Antibody to)
Alternative techniqueantibodies

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