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SET07 (43AT551.86) Monoclonal Antibody

SET07 (43AT551.86) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name86) Monoclonal Antibody, SET07 (43AT551
Also known as86) Monoclonal Antibody, SET07 (43AT551
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSET07
SpecificityThis is a highly specific antibody against SET07
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number43AT551, 86
SourceThis SET07 antibody was raised using purified recombinant GST fusion protein encoding the N-terminal region of human SET07
Gene ID number387893
Swiss ProtQ9NQR1
Tested Applications IF, IHC-P, WB
Recommended dilutions IF(1:10~50), IHC-P(1:10~50), WB(1:1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression, Involved in chromosome condensation and proper cytokinesis, Mainly functions in euchromatin regions, Mediates monomethylation of p53/TP53 at 'Lys-382', Nucleosomes are preferred as substrate compared to free histones, Plays a negative role in TGF-beta response regulation and a positive role in cell migration, Required for cell proliferation, Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1), leading to repress p53/TP53-target genes, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis, thereby playing a central role in the silencing of euchromatic genes, Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names H4-K20-HMTase KMT5A, Histone-lysine N-methyltransferase KMT5A, KMT5A, Lysine N-methyltransferase 5A, Lysine-specific methylase 5A, N-lysine methyltransferase KMT5A, PR-Set7, PR/SET domain-containing protein 07, PR/SET07, PRSET7, SET domain-containing protein 8, SET07, SETD8, SET8
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target86) Monoclonal, SET07 (43AT551
Short name86) Monoclonal Antibody, SET07 (43AT551
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name86) monoclonal (Antibody to), SET07 (43AT551
Alternative techniqueantibodies
Identity 29489
Gene KMT5A
Long gene name lysine methyltransferase 5A
Synonyms gene SETD8
Synonyms gene name SET domain containing (lysine methyltransferase) 8 lysine (K)-specific methyltransferase 5A
Synonyms SET8 SET07 PR-Set7
Locus 12q24, 31
Discovery year 2006-02-15
GenBank acession AY102937
Entrez gene record 387893
Pubmed identfication 15933070 12086618 12121615
RefSeq identity NM_020382
Classification Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000150477

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