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SFRP4 Antibody

SFRP4 Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSFRP4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, ELISA: suitable, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the SFRP4 antibody should be determined by the researcher
Intented useThis SFRP4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q6FHJ7
PurityAntigen affinity
Description And SFRP4 is a hub gene in a Type 2 Diabetes-associated gene coexpression module in human islets, It is mapped to 7p14, The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression, and reduces glucose-induced insulin secretion through decreased ?-cell exocytosis, 1, Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins
ImmunogenAmino acids 22-303 of human SFRP4 were used as the immunogen for the SFRP4 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SFRP4 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
LocalizationCytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSFRP4
Short nameSFRP4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesecreted frizzled-related protein 4 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target FRP-4 and FRPHE and sFRP-4, SFRP4 and IDBG-12815 and ENSG00000106483 and 6424, SFRP4 and IDBG-632677 and ENSBTAG00000015366 and 518004, Sfrp4 and IDBG-132703 and ENSMUSG00000021319 and 20379, Wnt-activated receptor activity, nuclei, this GO :0001944 and vasculature development and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007420 and brain development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008406 and this GO nad development and biological process this GO :0009725 and response to hormone and biological process this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0017147 and Wnt-protein binding and molecular function this GO :0022601 and menstrual cycle phase and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0045606 and positive regulation of epidermal cell differentiation and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046697 and decidualization and biological process this GO :0055062 and phosphate ion homeostasis and biological process this GO :0060056 and mammary gland involution and biological process this GO :0060429 and epithelium development and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :1902174 and positive regulation of keratinocyte apoptotic process and biological process this GO :2000119 and negative regulation of sodium-dependent phosphate transport and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0017147: Wnt-protein binding and also this GO :0030165: PDZ domain binding and also this GO :0042813: Wnt-activated receptor activity, this GO :0017147: Wnt-protein binding, this GO :0030165: PDZ domain binding, this GO :0042813: Wnt-activated receptor activity, secreted frizzled-related protein 4
Identity 10778
Gene SFRP4
Long gene name secreted frizzled related protein 4
Synonyms gene name secreted frizzled-related protein 4
Synonyms frpHE FRP-4 FRPHE
Locus 7p14, 1
Discovery year 1998-07-15
GenBank acession AF026692
Entrez gene record 6424
Pubmed identfication 10211996
RefSeq identity NM_003014
Classification Secreted frizzled-related proteins
Havana BLAST/BLAT OTTHUMG00000023026

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