Name : SFRP4 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN2321872095
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | SFRP4 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, ELISA: suitable, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the SFRP4 antibody should be determined by the researcher |
| Intented use | This SFRP4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q6FHJ7 |
| Purity | Antigen affinity |
| Description | And SFRP4 is a hub gene in a Type 2 Diabetes-associated gene coexpression module in human islets, It is mapped to 7p14, The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression, and reduces glucose-induced insulin secretion through decreased ?-cell exocytosis, 1, Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins |
| Immunogen | Amino acids 22-303 of human SFRP4 were used as the immunogen for the SFRP4 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SFRP4 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | SFRP4 |
| Short name | SFRP4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | secreted frizzled-related protein 4 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | FRP-4 and FRPHE and sFRP-4, SFRP4 and IDBG-12815 and ENSG00000106483 and 6424, SFRP4 and IDBG-632677 and ENSBTAG00000015366 and 518004, Sfrp4 and IDBG-132703 and ENSMUSG00000021319 and 20379, Wnt-activated receptor activity, nuclei, this GO :0001944 and vasculature development and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007420 and brain development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008406 and this GO nad development and biological process this GO :0009725 and response to hormone and biological process this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0017147 and Wnt-protein binding and molecular function this GO :0022601 and menstrual cycle phase and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0045606 and positive regulation of epidermal cell differentiation and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046697 and decidualization and biological process this GO :0055062 and phosphate ion homeostasis and biological process this GO :0060056 and mammary gland involution and biological process this GO :0060429 and epithelium development and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :1902174 and positive regulation of keratinocyte apoptotic process and biological process this GO :2000119 and negative regulation of sodium-dependent phosphate transport and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0017147: Wnt-protein binding and also this GO :0030165: PDZ domain binding and also this GO :0042813: Wnt-activated receptor activity, this GO :0017147: Wnt-protein binding, this GO :0030165: PDZ domain binding, this GO :0042813: Wnt-activated receptor activity, secreted frizzled-related protein 4 |
| Identity | 10778 |
| Gene | SFRP4 |
| Long gene name | secreted frizzled related protein 4 |
| Synonyms gene name | secreted frizzled-related protein 4 |
| Synonyms | frpHE FRP-4 FRPHE |
| Locus | 7p14, 1 |
| Discovery year | 1998-07-15 |
| GenBank acession | AF026692 |
| Entrez gene record | 6424 |
| Pubmed identfication | 10211996 |
| RefSeq identity | NM_003014 |
| Classification | Secreted frizzled-related proteins |
| Havana BLAST/BLAT | OTTHUMG00000023026 |