| Long name | SGK1 (Ser422) Primary Polyclonal Antibody |
| Also known as | SGK1 (Ser422) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SGK1 Ser422 |
| Specificity | This is a highly specific antibody against SGK1 Ser422 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser422 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 400-431/431 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser422 |
| Gene ID number | 6446 |
| Swiss Prot | O00141 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy, Jan 2009], Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene, This kinase activates certain potassium, [provided by RefSeq, and chloride channels, and renal sodium excretion, neuronal excitability, sodium, suggesting an involvement in the regulation of processes such as cell survival, This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | SGK1, Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, SGK |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SGK1 (Ser422) |
| Short name | SGK1 (Ser422) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | serum/glucocorticoid regulated kinase 1 (Ser422) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | SGK, SGK1 and IDBG-633483 and ENSBTAG00000004269 and 515854, SGK1 and IDBG-96775 and ENSG00000118515 and 6446, Sgk1 and IDBG-137283 and ENSMUSG00000019970 and 20393, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0006950 and response to stress and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007616 and long-term memory and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004712: protein serine/threonine/tyrosine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005246: calcium channel regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0015459: potassium channel regulator activity and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004712: protein serine/threonine/tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005246: calcium channel regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0015459: potassium channel regulator activity, this GO :0016772: transferase activity, this GO :0017080: sodium channel regulator activity, this GO :0017081: chloride channel regulator activity, this GO :0035091: phosphatidylinositol binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080: sodium channel regulator activity and also this GO :0017081: chloride channel regulator activity and also this GO :0035091: phosphatidylinositol binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0017081 and chloride channel regulator activity and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0032411 and positive regulation of transporter activity and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042127 and regulation of cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060453 and regulation of gastric acid secretion and biological process this GO :0070294 and renal sodium ion absorption and biological process, serum/glucocorticoid regulated kinase 1 |
| Identity | 10810 |
| Gene | SGK1 |
| Long gene name | serum/glucocorticoid regulated kinase 1 |
| Synonyms gene | SGK |
| Synonyms gene name | serum/glucocorticoid regulated kinase |
| Locus | 6q23, 2 |
| Discovery year | 1997-06-12 |
| GenBank acession | AJ000512 |
| Entrez gene record | 6446 |
| Pubmed identfication | 9114008 9722955 |
| Havana BLAST/BLAT | OTTHUMG00000015613 |
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