| Long name | SGK3 Primary Polyclonal Antibody |
| Also known as | SGK3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SGK3 |
| Specificity | This is a highly specific antibody against SGK3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 40-90/496 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SGK3 |
| Gene ID number | 23678 |
| Swiss Prot | Q96BR1 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | K(+) channels: KCNA3/KV1, KCNE1, KCNQ1 and KCNH2/HERG, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, Na(+)/H(+) exchanger: SLC9A3/NHE3, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes, Phosphorylates NEDD4L and GSK3B, Plays a role in the regulation of renal tubular phosphate transport and bone density, Positively regulates ER transcription activity through phosphorylation of FLII, SLC1A6/EAAT4 and SLC1A7/EAAT5, Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, and the Na(+)/K(+) ATPase, cell growth, chloride channel: BSND, creatine transporter: SLC6A8, epithelial Ca(2+) channels: TRPV5 and TRPV6, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, glutamate transporters: SLC1A3/EAAT1, membrane transporters, proliferation, survival and migration, 3, Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Cytokine-independent survival kinase, SGK2, SGK3, SGKL, Serine/threonine-protein kinase Sgk3, Serum/glucocorticoid-regulated kinase 3, Serum/glucocorticoid-regulated kinase-like, CISK |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SGK3 |
| Short name | SGK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member 3 (Antibody to), serum/glucocorticoid regulated kinase family |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, SGK3 and IDBG-23987 and ENSG00000104205 and 100533105, member 3, this GO :0001558 and regulation of cell growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005769 and early endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005246: calcium channel regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0015459: potassium channel regulator activity and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005246: calcium channel regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0015459: potassium channel regulator activity, this GO :0016772: transferase activity, this GO :0017080: sodium channel regulator activity, this GO :0017081: chloride channel regulator activity, this GO :0035091: phosphatidylinositol binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080: sodium channel regulator activity and also this GO :0017081: chloride channel regulator activity and also this GO :0035091: phosphatidylinositol binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0017081 and chloride channel regulator activity and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042127 and regulation of cell proliferation and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0055037 and recycling endosome and cellular component this GO :0055085 and transmembrane transport and biological process, 23678, serum/glucocorticoid regulated kinase family |
| Identity | 10812 |
| Gene | SGK3 |
| Long gene name | serum/glucocorticoid regulated kinase family member 3 |
| Synonyms gene | SGK2 SGKL |
| Synonyms gene name | member 3 , serum/glucocorticoid regulated kinase-like serum/glucocorticoid regulated kinase family |
| Locus | 8q13, 1 |
| Discovery year | 1999-08-12 |
| Entrez gene record | 23678 |
| Pubmed identfication | 10585774 10548550 |
| Havana BLAST/BLAT | OTTHUMG00000164561 |
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