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SGSH/Sulphamidase Antibody

SGSH/Sulphamidase Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSGSH/Sulphamidase Primary Polyclonal Antibody
Also known asSGSH/Sulphamidase PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSGSH/Sulphamidase
SpecificityThis is a highly specific antibody against SGSH/Sulphamidase
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range310-360/502
Subcellular locationLysosome
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sulphamidase
Gene ID number6448
Swiss ProtP51688
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids, It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate, MPS3A or SGSH, SFMD, Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations, Sulfamidase, also known as HSS, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate, is a 502 amino acid lysosome that belongs to the sulfatase family, Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MPS3A, N-sulphoglucosamine sulphohydrolase, SFMD, SGSH, Sulfoglucosamine sulfamidase, Sulphamidase, HSS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSGSH/Sulphamidase
Short nameSGSH/Sulphamidase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSGSH/Sulphamidase (Antibody to)
Alternative techniqueantibodies
Identity 10818
Gene SGSH
Long gene name N-sulfoglucosamine sulfohydrolase
Synonyms HSS MPS3A SFMD
Synonyms name sulfamidase mucopolysaccharidosis type IIIA
Locus 17q25, 3
Discovery year 1997-06-24
GenBank acession BC047318
Entrez gene record 6448
Pubmed identfication 7493035
RefSeq identity NM_000199
Classification Sulfatases
Havana BLAST/BLAT OTTHUMG00000177569

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