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SGSH/Sulphamidase Antibody, ALEXA FLUOR 488

SGSH/Sulphamidase Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, SGSH/Sulphamidase Polyclonal Antibody
Also known asAnti-SGSH/Sulphamidase PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSGSH/Sulphamidase
SpecificityThis is a highly specific antibody against SGSH/Sulphamidase
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range310-360/502
Subcellular locationLysosome
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sulphamidase
Gene ID Number6448
Swiss ProtP51688
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids, It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate, MPS3A or SGSH, SFMD, Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations, Sulfamidase, also known as HSS, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate, is a 502 amino acid lysosome that belongs to the sulfatase family, Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms HSS MPS3A SFMD
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SGSH/Sulphamidase Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSGSH/Sulphamidase
Short nameSGSH/Sulphamidase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, SGSH/Sulphamidase (Antibody to)
Alternative techniqueantibodies
Identity 10818
Gene SGSH
Long gene name N-sulfoglucosamine sulfohydrolase
Synonyms name sulfamidase mucopolysaccharidosis type IIIA
Locus 17q25, 3
Discovery year 1997-06-24
GenBank acession BC047318
Entrez gene record 6448
Pubmed identfication 7493035
RefSeq identity NM_000199
Classification Sulfatases
Havana BLAST/BLAT OTTHUMG00000177569

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