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SH3KBP1 Antibody, FITC Conjugated

SH3KBP1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, SH3KBP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSH3KBP1
SpecificityThis is a highly specific antibody against SH3KBP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SH3KBP1
Gene ID number30011
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alternate splicing results in multiple transcript variants, In the case of EGF receptor turnover, Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation, SH3KBP1 is involved in regulating diverse signal transduction pathways, The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases, a proline rich region and a C-terminal coiled-coil domain, characterized by containing three N-terminal Src homology domains, including EGFR and MET/hepatocyte growth factor receptor, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization, through a association with CBL and endophilins, SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CIN85
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSH3KBP1 Conjugated
Short name FITC Conjugated, SH3KBP1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SH3-domain phosphorylation catalyst binding protein 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, Cell surfaces, SH3 domain binding, SH3KBP1 and IDBG-49936 and ENSG00000147010 and 30011, Sh3kbp1 and IDBG-182475 and ENSMUSG00000040990 and 58194, this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006897 and endocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0016301 and kinase activity and molecular function this GO :0016310 and phosphorylation and biological process this GO :0016477 and cell migration and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0043005 and neuron projection and cellular component this GO :0045202 and synapse and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0016301: kinase activity and also this GO :0017124: SH3 domain binding, this GO :0016301: kinase activity, this GO :0017124: SH3 domain binding, 104277 and IDBG-638563 and ENSBTAG00000003727 and 510489, SH3-domain kinase binding protein 1
Identity 13867
Gene SH3KBP1
Long gene name SH3 domain containing kinase binding protein 1
Locus Xp22, 12
Discovery year 2000-12-14
GenBank acession AF230904
Entrez gene record 30011
Pubmed identfication 8889549 7566098
RefSeq identity NM_031892
Havana BLAST/BLAT OTTHUMG00000021227
Locus Specific Databases Mental Retardation database

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