Name : SH3TC2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6362147714
| Long name | SH3TC2 Primary Polyclonal Antibody |
| Also known as | SH3TC2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SH3TC2 |
| Specificity | This is a highly specific antibody against SH3TC2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SH3TC2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene, Existing as four alternatively spliced isoforms and containing 18 exons, Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene, The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, The SH3TC2 protein is expressed in adult heart, and brain as well as in fetal brain and liver, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, and maps to human chromosome 5q32, chicken and zebrafish, cow, dog, mouse, rat, spinal cord, suggesting a possible function in myelination and/or in regions of axoglial interactions, testis, the SH3TC2 gene is conserved in chimpanzee, 288 amino acid protein that contains one SH3 domain and eight TPR repeats, SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CMT4C, D430044G18Rik, FLJ13605, MNMN, PP12494, RGD1309038, S3TC2_HUMAN, SH3 domain and tetratricopeptide repeats-containing protein 2, SH3TC2, KIAA1985 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SH3TC2 |
| Short name | SH3TC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SH3TC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29427 |
| Gene | SH3TC2 |
| Long gene name | SH3 domain and tetratricopeptide repeats 2 |
| Synonyms | KIAA1985 CMT4C |
| Locus | 5q32 |
| Discovery year | 2004-12-15 |
| GenBank acession | AK127248 |
| Entrez gene record | 79628 |
| Pubmed identfication | 14574644 |
| RefSeq identity | NM_024577 |
| Classification | Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000129930 |
| Locus Specific Databases | Inherited Peripheral Neuropathies Mutation Database LRG_269 |