Filters

SHANK3 Antibody

SHANK3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSHANK3 Primary Polyclonal Antibody
Also known asSHANK3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSHANK3
SpecificityThis is a highly specific antibody against SHANK3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1165-1215/1741
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHANK3
Gene ID number85358
Swiss ProtQ9BYB0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity, By way of this control of actin dynamics, Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation, Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters, and the actin-based cytoskeleton, maturation and maintenance, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling, respectively, Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DEL22q13, KIAA1650, PROSAP2, Proline-rich synapse-associated protein 2, SCZD15, SH3 and multiple ankyrin repeat domains protein 3, SPANK-2, Shank3, 3, PSAP2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSHANK3
Short nameSHANK3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSHANK3 (Antibody to)
Alternative techniqueantibodies
Identity 14294
Gene SHANK3
Long gene name SH3 and multiple ankyrin repeat domains 3
Synonyms SPANK-2 prosap2 KIAA1650 PSAP2
Synonyms name proline rich synapse associated protein 2 shank postsynaptic density protein
Locus 22q13, 33
Discovery year 2002-02-22
GenBank acession AB051437
Entrez gene record 85358
Pubmed identfication 11258795 11431708 10806096 17173049
RefSeq identity NM_001080420
Classification Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000150169

Similar products

Subscribe to our Newsletter