Name : SHANK3 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8364368971
| Long name | ALEXA FLUOR 647 Conjugated, SHANK3 Polyclonal Antibody |
| Also known as | Anti-SHANK3 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SHANK3 |
| Specificity | This is a highly specific antibody against SHANK3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1165-1215/1741 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHANK3 |
| Gene ID Number | 85358 |
| Swiss Prot | Q9BYB0 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity, By way of this control of actin dynamics, Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation, Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters, and the actin-based cytoskeleton, maturation and maintenance, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling, respectively, Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | SPANK-2 prosap2 KIAA1650 PSAP2 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SHANK3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | SHANK3 |
| Short name | SHANK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, SHANK3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14294 |
| Gene | SHANK3 |
| Long gene name | SH3 and multiple ankyrin repeat domains 3 |
| Synonyms name | proline rich synapse associated protein 2 shank postsynaptic density protein |
| Locus | 22q13, 33 |
| Discovery year | 2002-02-22 |
| GenBank acession | AB051437 |
| Entrez gene record | 85358 |
| Pubmed identfication | 11258795 11431708 10806096 17173049 |
| RefSeq identity | NM_001080420 |
| Classification | Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000150169 |