Filters

SHANK3 Antibody, Biotin Conjugated

SHANK3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SHANK3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHANK3
SpecificityThis is a highly specific antibody against SHANK3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1165-1215/1741
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human SHANK3
Gene ID number85358
Swiss ProtQ9BYB0
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity, By way of this control of actin dynamics, Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation, Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters, and the actin-based cytoskeleton, maturation and maintenance, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling, respectively, Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms SPANK-2 prosap2 KIAA1650 PSAP2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSHANK3 Conjugated
Short name Conjugated, SHANK3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SHANK3 (Antibody to)
Alternative techniqueantibodies
Identity 14294
Gene SHANK3
Long gene name SH3 and multiple ankyrin repeat domains 3
Synonyms name proline rich synapse associated protein 2 shank postsynaptic density protein
Locus 22q13, 33
Discovery year 2002-02-22
GenBank acession AB051437
Entrez gene record 85358
Pubmed identfication 11258795 11431708 10806096 17173049
RefSeq identity NM_001080420
Classification Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000150169

Similar products

Subscribe to our Newsletter