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SHANK3 Antibody, Cy5 Conjugated

SHANK3 Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, SHANK3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHANK3
SpecificityThis is a highly specific antibody against SHANK3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1165-1215/1741
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human SHANK3
Gene ID number85358
Swiss ProtQ9BYB0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity, By way of this control of actin dynamics, Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation, Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters, and the actin-based cytoskeleton, maturation and maintenance, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling, respectively, Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms SPANK-2 prosap2 KIAA1650 PSAP2
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSHANK3 Conjugated
Short name Conjugated, SHANK3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, SHANK3 (Antibody to)
Alternative techniqueantibodies
Identity 14294
Gene SHANK3
Long gene name SH3 and multiple ankyrin repeat domains 3
Synonyms name proline rich synapse associated protein 2 shank postsynaptic density protein
Locus 22q13, 33
Discovery year 2002-02-22
GenBank acession AB051437
Entrez gene record 85358
Pubmed identfication 11258795 11431708 10806096 17173049
RefSeq identity NM_001080420
Classification Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000150169

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