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SHARPIN Antibody, ALEXA FLUOR 555

SHARPIN Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, SHARPIN Polyclonal Antibody
Also known asAnti-SHARPIN PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHARPIN
SpecificityThis is a highly specific antibody against SHARPIN
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range260-310/387
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHARPIN
Gene ID Number81858
Swiss ProtQ9H0F6
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways, LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex, Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation, Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis, Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms DKFZP434N1923 SIPL1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetSHARPIN
Short nameSHARPIN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, SHARPIN (Antibody to)
Alternative techniqueantibodies
Identity 25321
Gene SHARPIN
Long gene name SHANK associated RH domain interactor
Locus 8q24, 3
Discovery year 2005-08-09
GenBank acession AL136816
Entrez gene record 81858
Pubmed identfication 11178875 12753155
RefSeq identity NM_030974
Classification Zinc fingers RANBP2-type Linear ubiquitin chain assembly complex
Havana BLAST/BLAT OTTHUMG00000165243

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