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SHC(Tyr349) Antibody, Cy7 Conjugated

SHC(Tyr349) Antibody, Cy7 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, SHC(Tyr349) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHC Tyr349
SpecificityThis is a highly specific antibody against SHC Tyr349
ModificationPhosphorylation
Modification siteTyr349
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human SHC around the phosphorylation site of Tyr349
Gene ID number6464
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Adjacent to the SH2 region is a glycine and proline rich region, SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway, The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways, These 2 proteins differ in their N terminals, both containing a C-terminal SH2 domain, The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms p66 ShcA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetSHC(Tyr349) Conjugated
Short name Conjugated, SHC(Tyr349) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, SHC(Tyr349) (Antibody to)
Alternative techniqueantibodies
Identity 10840
Gene SHC1
Long gene name SHC adaptor protein 1
Synonyms gene SHC
Synonyms gene name SHC (Src homology 2 domain-containing) transforming protein 1
Locus 1q21, 3
Discovery year 1993-02-17
GenBank acession U73377
Entrez gene record 6464
Pubmed identfication 1623525
RefSeq identity NM_183001
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000037295

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