Filters

Shc1 (47F4) Monoclonal Antibody

Shc1 (47F4) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameShc1 (47F4) Monoclonal Antibody
Also known asShc1 (47F4) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenShc1
SpecificityThis is a highly specific antibody against Shc1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number47F4
Concentration1ug per 1ul
SourceRecombinant human protein purified from E, coli (His/ABD-Shc1) 
Gene ID number6464
Swiss ProtP29353
Tested Applications IP, WB
Recommended dilutions0 ug), 1 ug/ml) IP (2, WB (0
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Isoform p46Shc and isoform p52Shc, Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems, Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, Isoform p66Shc does not mediate Ras activation, Participates in a signaling cascade initiated by activated KIT and KITLG/SCF, Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, The expression of isoform p66Shc has been correlated with life span (By similarity), and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals, cytochrome c release and apoptosis, once phosphorylated, Signaling adapter that couples activated growth factor receptors to signaling pathways
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names SH2 domain protein C1, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A, SHC1, SHCA, Src homology 2 domain-containing-transforming protein C1, SHC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetShc1 (47F4) Monoclonal
Short nameShc1 (47F4) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameShc1 (47F4) monoclonal (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter