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SHC2/Sck Antibody, ALEXA FLUOR 350

SHC2/Sck Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, SHC2/Sck Polyclonal Antibody
Also known asAnti-SHC2/Sck PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHC2/Sck
SpecificityThis is a highly specific antibody against SHC2/Sck
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHC2/Sck
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Human Sck transcripts are present at high levels in liver, In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6), Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2, pancreas, prostate and ovary (4, 3), 5), 8), Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms SLI SCK SHCB
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetSHC2/Sck
Short nameSHC2/Sck Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, SHC2/Sck (Antibody to)
Alternative techniqueantibodies
Identity 29869
Gene SHC2
Long gene name SHC adaptor protein 2
Synonyms gene name SHC (Src homology 2 domain containing) transforming protein 2
Synonyms name neuronal Shc adaptor homolog
Locus 19p13, 3
Discovery year 2004-03-18
GenBank acession AB001451
Entrez gene record 25759
Pubmed identfication 7527937 9507002
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000180545

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