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SHC2/Sck Antibody, Cy3 Conjugated

SHC2/Sck Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, SHC2/Sck Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHC2/Sck
SpecificityThis is a highly specific antibody against SHC2/Sck
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SHC2/Sck
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Human Sck transcripts are present at high levels in liver, In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6), Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2, pancreas, prostate and ovary (4, 3), 5), 8), Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms SLI SCK SHCB
Properties 1 of the SHC2/Sck Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSHC2/Sck Conjugated
Short name Conjugated, SHC2/Sck Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, SHC2/Sck (Antibody to)
Alternative techniqueantibodies
Identity 29869
Gene SHC2
Long gene name SHC adaptor protein 2
Synonyms gene name SHC (Src homology 2 domain containing) transforming protein 2
Synonyms name neuronal Shc adaptor homolog
Locus 19p13, 3
Discovery year 2004-03-18
GenBank acession AB001451
Entrez gene record 25759
Pubmed identfication 7527937 9507002
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000180545

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