Name : SHFM3 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6257433922
| Long name | ALEXA FLUOR 488 Conjugated, SHFM3 Polyclonal Antibody |
| Also known as | Anti-SHFM3 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SHFM3 |
| Specificity | This is a highly specific antibody against SHFM3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHFM3 |
| Gene ID Number | 6468 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Likely to be involved in key signaling pathways crucial for normal limb development, May participate in Wnt signaling, SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits, Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) , Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | Fbw4 dactylin |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SHFM3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | SHFM3 |
| Short name | SHFM3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, SHFM3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10847 |
| Gene | FBXW4 |
| Long gene name | F-box and WD repeat domain containing 4 |
| Synonyms gene | SHFM3 |
| Synonyms gene name | split hand/foot malformation (ectrodactyly) type 3 F-box and WD-40 domain protein 4 |
| Locus | 10q24, 32 |
| Discovery year | 1994-09-26 |
| GenBank acession | AF281859 |
| Entrez gene record | 6468 |
| Pubmed identfication | 8723077 7912888 |
| RefSeq identity | NM_022039 |
| Classification | F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000018938 |