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SHFM3 Antibody, Biotin Conjugated

SHFM3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SHFM3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHFM3
SpecificityThis is a highly specific antibody against SHFM3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SHFM3
Gene ID number6468
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Likely to be involved in key signaling pathways crucial for normal limb development, May participate in Wnt signaling, SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits, Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) , Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Fbw4 dactylin
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSHFM3 Conjugated
Short name Conjugated, SHFM3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SHFM3 (Antibody to)
Alternative techniqueantibodies
Identity 10847
Gene FBXW4
Long gene name F-box and WD repeat domain containing 4
Synonyms gene SHFM3
Synonyms gene name split hand/foot malformation (ectrodactyly) type 3 F-box and WD-40 domain protein 4
Locus 10q24, 32
Discovery year 1994-09-26
GenBank acession AF281859
Entrez gene record 6468
Pubmed identfication 8723077 7912888
RefSeq identity NM_022039
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000018938

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